BARD1 deletion in a patient with suspected hereditary colorectal cancer

BARD1 deletion in a patient with suspected hereditary colorectal cancer

Blog Article

Abstract Deleterious germline variants in the BRCA1-associated ring domain (BARD1) gene moderately elevate breast cancer risk; however, their potential association with other neoplasms Loaf Pan remains unclear.Here, we present the case of a 43-year-old female patient diagnosed with sigmoid colon Driver Safety Supplies adenocarcinoma whose maternal family members met the Amsterdam Criteria II for Lynch syndrome.Comprehensive multigene panel testing revealed a heterozygous BARD1 exon 3 deletion.